Tramadol is a prescription medication used to treat moderate to severe pain. Although acne is not listed as a side effect of that Tramadol, all drugs can potentially affect acne-related hormones.
Please tell us about your experience with Tramadol. Be accurate and honest. Thanks.


I started taking tramadol, where before i never had acne and now i have it all on my face but nowhere else… So yes i do think it can cause acne……i could be break out but looks like acne.
I am taking ten different types of mediaction for three medical problems and have been for over three years. Within the past six months I have started to experience spots on my face and particularly inside the nose. I have never suffered with acne as a youth and only experienced sports if I had a period of time when I ate an excess of chocolate. This is not a food of choice and I generally eat what is considered to be a healthy diet. Considering the above I am concerned that the medication I am taking is cintributing to the discomfort I am having with spots. Tramadol is one of the treatments I am on.
I have taken Tramadol FOUR TIMES in the past 5-6 days for tooth pain and my face has exploded with acne. I’m almost 25, I rarely get acne anymore and if I do its usually just hormonal and once a month. I have to assume that the Tramadol was the reason as nothing else has changed in the past week or so. I literally took it four times and the result was enormous. I have to assume if you are taking it regularly and recently broke out when you normally did not that there is some (pretty strong in my opinion) correlation.
I STARTED TAKING TRAMADOL AND MY FACE. NECK AND CHEST ARE BREAKING OUT IN SMALL PIMPLES AND MY SKIN IS SO OILY I HAVE TO WASH IT SEVERAL TIMES TO GET IT CLEAR. THIS HAS HAPPENED BOTH TIMES I HAVE TAKEN THIS MEDICATION. ALTHOUGH THIS IS NOT A LISTED SIDE EFFECT IT SEEMS IN NOT THE ONLY ONE
hi there……Im a 54yr old male and have “problem” skin………yes. still getting pimples at my age!! I have been taking 200mg Tramadol daily for the past week and I now have a serious “breakout” of acne on my nose……I can only presume it’s the Tramadol causing this. Bugger! Just when I thought I had finally got on top of my pain!
my doctor just put me on tramadol yesterday afternoon and this morning i woke up with a spot on my chest. i don’t get acne except around that time of the month, and i certainly don’t get it on my body. it doesn’t appear poppable at all. i also got insane muscle twitches and couldn’t sleep all night.